Kinetic Analysis of High Affinity Antibody Antigen Interaction using Surface Plasmon Resonance
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چکیده
The determination of kinetic binding constants for antibody-antigen interactions is critical in many research and development applications. OpenSPR allows users to easily and accurately measure the binding kinetics of numerous ligand-antigen systems. In this application note, OpenSPR is used to determine the on and off rates and affinity constant for the interaction between prostate specific antigen (PSA) and its antibody (anti-PSA). Results are compared against industry standard surface plasmon resonance instruments.
منابع مشابه
Kinetic Analysis of High Affinity Antibody Antigen Interaction using Surface Plasmon Resonance
The determination of kinetic binding constants for antibody-antigen interactions is critical in many research and development applications. OpenSPR allows users to easily and accurately measure the binding kinetics of numerous ligand-antigen systems. In this application note, OpenSPR is used to determine the on and off rates and affinity constant for the interaction between prostate specific an...
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